Desitin Maximum Strength Baby Diaper Rash Cream, 40% Zinc Oxide for Treatment, Relief & Prevention, Hypoallergenic, Phthalate

4.8 4.8 out of 5 stars | 46,362 ratings

Price: 19.48

Last update: 12-02-2025


About this item

  • 16-ounce jar of Desitin Maximum Strength Diaper Rash Paste with 40% zinc oxide works on contact to treat and help prevent baby diaper rash discomfort
  • Rich, thick diaper rash cream is formulated with 40% maximum-level zinc oxide and is clinically shown to protect baby's delicate skin for up to 12 hours
  • The maximum strength paste provides effective diaper rash relief by immediately forming a protective barrier on baby's skin to seal out wetness and soothe chafed skin
  • The baby diaper rash paste's hypoallergenic formula is paraben-, phthalate-, and dye-free. It is also Dermatologist- and Pediatrician-tested and is gentle enough for daily use
  • Maximum strength diaper rash paste provides 5-in-1 action to treat, heal, protect, soothe & help prevent diaper rash, for healing you can see & relief your baby can feel. Apply paste as often as needed or when exposure to wet diapers may be prolonged

  • Is Discontinued By Manufacturer ‏ : ‎No
  • Product Dimensions ‏ : ‎3.2 x 3.5 x 3.2 inches; 1 Pounds
  • Item model number ‏ : ‎J&J048975
  • Date First Available ‏ : ‎September 26, 2008
  • Manufacturer ‏ : ‎Kenvue
  • ASIN ‏ : ‎B00BH0PZBG
  • Best Sellers Rank:#1,578 in Health & Household (See Top 100 in Health & Household)
    • Diaper Creams
    • Sales & Deals
  • Customer Reviews:
    4.84.8 out of 5 stars(46,361)

Top reviews from the United States

  • A household essential that heals fast and protects even better
    A household essential that heals fast and protects even better

    Desitin Maximum Strength Diaper Rash Cream has been around for decades for a reason—it simply works. The 40% zinc oxide formula is thick, soothing, and forms an instant protective barrier that seals out moisture and promotes healing. It’s the go-to for stubborn rashes that other creams can’t touch, often clearing irritation within a day or two.

    The cream’s texture is dense but spreads evenly, staying in place through multiple diaper changes or overnight use. It’s gentle enough for newborns yet strong enough for adults dealing with chafing or skin irritation from incontinence pads, sweat, or friction. Because it’s hypoallergenic and free of parabens, phthalates, and dyes, it rarely causes irritation even on sensitive skin.

    The 16-ounce tub is great value—it lasts for months and is far more economical than small tubes. The only minor drawback is that the paste can be hard to remove completely from skin or fabric if overapplied, and it has a mild medicinal scent that not everyone loves.

    Bottom line: a trusted, dermatologist-tested classic that lives up to its reputation. If you need fast, reliable relief for diaper rash, chafing, or general skin irritation, Desitin Maximum Strength remains the gold standard for both babies and adults alike.
  • Excellent Protection for Baby’s Skin!
    Desitin Maximum Strength Diaper Rash Cream is a lifesaver for my baby’s sensitive skin. It works fast — I noticed a big improvement after just one or two diaper changes. The thick formula creates a strong barrier that protects against moisture and irritation, and it stays in place really well. A little goes a long way, so the tube lasts quite a while. The smell is mild and pleasant, and it gives me peace of mind knowing my baby is comfortable and rash-free. Definitely a must-have for every diaper bag!
  • The best diaper cream
    Destin is the only thing that works for my kids. We all know that these diapers are full of chemicals that causes these rashes to appear. When i plaster that Destin all over my baby, no rash, no discomfort. No sores.
  • Best Diaper Ointment
    I’ve tried several diaper ointments over the years, but this one truly stands out. The texture is smooth and easy to apply, and it creates a protective barrier without feeling too thick or sticky. Within just a couple of uses, I noticed a big difference....If you’re a parent looking for something reliable, soothing, and effective, this diaper ointment is definitely worth it. I highly recommend it!
  • Reliable Diaper Rash Relief That Works Fast
    Desitin Maximum Strength has been my go-to diaper rash cream for years, and it continues to be one of the most effective options I’ve tried. The thick, rich formula with 40% zinc oxide creates a strong barrier that protects the skin and starts soothing almost immediately. It’s especially helpful during overnight changes or when my baby has a particularly irritated rash—it noticeably reduces redness and discomfort by the next diaper change, often within hours.

    I like that it’s hypoallergenic and free from added parabens and dyes, which gives me more confidence using it on sensitive skin. There’s a noticeable difference in how quickly rashes clear up compared to milder creams. It’s definitely on the thicker side, so it takes a little more effort to spread and remove, but that’s also what makes it so effective—it stays in place and doesn’t wear off too quickly.

    The 4.8 oz tube is a generous size and lasts quite a while, even with regular use. It’s also a good size to keep in the diaper bag without taking up too much space.

    If you're dealing with anything more than mild irritation, this is the kind of product that actually makes a difference. It’s not fancy, but it’s reliable, safe, and it works—which is exactly what I want in a diaper rash cream.
  • Better than Boudreaux's Butt Paste... Lasts FOREVER.
    Recommended by our pediatrician. We use this several times a week, with several applications per day of use. Lasts forever... baby is 17 months, and we are still using the same jar that we opened when she was a newborn. Works 10x better than Boudreaux's Butt Paste. BUY THIS.
  • It works well compared to many.
    It really helps compared to quite a few like A&D Ointment kind.
  • A Wonderful morning adjunct to my day
    Oh so grateful for this -- it keeps ME -- a large human being, from having to do a little Chafe Dance on my way to the bus every morning.
    Decent price, lasts long cuz I only needf to use a little -- smooth, unscented i think-- jut makes my life So Much Better

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