Immune: A Journey into the Mysterious System That Keeps You Alive
4.8 4.8 out of 5 stars | 8,760 ratings
Price: 17.72
Last update: 12-24-2024
About this item
A deep dive into the immune system that will forever change how you think about your body, from the creator of the popular science YouTube channel Kurzgesagt - In a Nutshell.
“Through wonderful analogies and a genius for clarifying complex ideas, Immune is a truly brilliant introduction to the human body’s vast system for fighting infections and other threats.” (John Green, number one New York Times best-selling author of The Fault in Our Stars)
You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door.
So what, exactly, is your immune system?
Second only to the human brain in its complexity, it is one of the oldest and most critical facets of life on Earth. Without it, you would die within days. In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defenses. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you’ve been reading this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body.
Each chapter delves into an element of the immune system, including defenses like antibodies and inflammation as well as threats like bacteria, allergies, and cancer, as Dettmer reveals why boosting your immune system is actually nonsense, how parasites sneak their way past your body’s defenses, how viruses work, and what goes on in your wounds when you cut yourself.
Enlivened by immersive descriptions, Immune turns one of the most intricate, interconnected, and confusing subjects - immunology - into a gripping adventure through an astonishing alien landscape. Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.
Top reviews from the United States
5.0 out of 5 stars Great Overview, Streamlined, Intelligent, Funny, and a Criticism of Criticism
The information is solid, researched focused, and is based on staying within the realm of what is certain, while staying keen on underscoring the speculative. Dettmer deploys the narrative style of explanation, which is conducive to a coherent communication of a big picture for a topic that is unfortunately riddled with canyon-sized rabbit holes. If you struggle to direct your attention while reading, either because of a loss of pace or an excess of dry reading, you are especially catered to here. Delightful and appropriate instances of humor decorate sincere moments of education. Further, Dettmer successfully utilizes the educational form of explaining the very basics first to later elucidate topics that are relatable in common life, rather than diving head first into the complexities from the get go. As Dettmer cautiously mentions, this book doesn't scratch the surface, but upon its completion you'll know much more than the average person.
I saw a couple reviews here that criticize his tendency to anthropomorphize while at once warning against the uncritical acceptance of the same idea. Another criticism brought up regards a discussion of stress and implies that the author encourages readers to dig themselves into holes whenever stress appears. I believe these criticisms are unfounded. Even at the undergraduate level, analogy, metaphor- yes even by anthropomorphizing, and anecdote are all didactic tools used to explain to the very novice the beginnings of a topic. As students learn, the simplifications and subtle lies are dispelled and the ugly truth is slowly revealed. Often, beginners can't handle the whole truth all at once and that should be clear here, as its constantly implied by the author. The book is not intended for advanced study, and that's obvious. If you buy this book thinking that your experience in immunology will be tantamount to that of an immunologist, you are wrong. If you buy this book expecting a university-style series of lectures whereby all the casual oversimplifications are disposed of, you are wrong. If you buy this book expecting anything other than a cursory glance at a complex topic, you are sorely mistaken. Criticisms against these discrepancies don't honestly and earnestly represent the intentions of the author or the content of the book. In addition, no- Dettmer does not suggest that the best remedy to stress is to hide in a hole, and the suggestion that you can simply adapt your immune system to cope with stress is a misunderstanding of the very content upon which the criticism was made. Instead, a notion is put forward that by maintaining a healthy and low-stress lifestyle, your immune system receives all the support it needs rather than depending on fraudulent supplementation. There's no suggestion that the reader should evade stress entirely and the claim that there is lacks veracity.
Lastly, any criticisms against this book for its marked 'political' influences are rooted in their own biases from the get go. Upon reading the book, you'll pleasantly find that there is not a single mention of American or any politics, given that the author is German and trying to tell you about cells. One reviewer notes an apparent 99.9% survival rate of COVID19 as evidence for criticism against the statement by the author that SARS-CoV2 is deadly. This 99.9% supposed survival rate in turn indicates a 0.1% mortality rate. Out of the now 568,773,510 cumulative cases, that's a little over half a million cumulative deaths, more than both SARS1 2003 outbreak and MERS outbreak combined, two much more lethal viruses. Not only this, but the real life (and based on actual data) number of deaths due to COVID-19 is in the ball park of more than six million people in about three years. An average of two million people a year. I think it's safe to say that the virus is deadly and such criticism against the statement is untenable. Besides, why wouldn't you want to learn how your body protects itself from such a pathogen?
5.0 out of 5 stars Like a spiritual book for me!
5.0 out of 5 stars In a Nutshell
In Immune, you'll learn about everything from macrophages to the thymus. You'll learn interesting things like how infected cells release cytokines, and while these are what lead to inflammation, these are also part of an incredible cascade that activates other parts of your immune system. (If cytokines freak you out, wait until you learn about what neutrophils can do.)
You'll also learn some surprising things. For example, there's no real way to "boost" your immune system, and you wouldn't want to even if you could! As it turns out, our immune systems can be pretty aggressive, and for the most part the balance between activation and deactivation can be a delicate thing. Your immune system, if over-activated, can actually hurt you...which makes sense if you think about allergies and autoimmune disorders.
If you want a "boosted" immune system, the best thing you can do is eat an at least OK diet, exercise, and manage your stress.
Another thing that struck me is how a lot of the immune system feels random. Yes, there are receptors, proteins, etc that different cells react to, but considering how small they are compared to us, it almost feels lucky that these different cells can meet at all. Of course, your heart pumps your blood around, so that helps, but it's just striking how something so effective can have no sentience or sapience.
The chapter on how vaccines work was very informative. The entire book is informative and wonderful to read (minus the author's tendency to use "in a nutshell" everywhere). This isn't one of those stuffy books where you feel like you're reading a college textbook. You'll learn about the immune system through various metaphors, such as battlegrounds and hotdog buns.
A fantastic book. Worth every penny and minute spent on it.