Similac 360 Total Care Infant Formula, Has 5 HMO Prebiotics, Our Closest Prebiotic Blend to Breast Milk, Non-GMO, Baby Formul
4.7 | 7,652 ratings
Price: 43.16
Last update: 01-22-2026
About this item
- CLOSER TO BREAST MILK THAN EVER BEFORE: Similac 360 Total Care, our biggest formula breakthrough, has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk
- 360 WHOLE-BABY SUPPORT: Nutrition designed for immune support, brain development, and digestive health
- HELPS STRENGTHEN THE IMMUNE SYSTEM: Similac 360 Total Care is designed to help strengthen baby’s immune system
- CONVENIENT & READY TO USE: Great for on-the-go and late-night feeding; no mixing required
- TRUSTED BRAND: Similac is the #1 infant formula brand chosen by parents
- Product Dimensions : 1.76 x 1.76 x 4.31 inches; 10.1 Pounds
- Date First Available : August 31, 2021
- Manufacturer : Abbott Laboratories
- ASIN : B09F5WVMHV
- Best Sellers Rank:#52 in Baby (See Top 100 in Baby)
- Liquid Baby Formula
- Customer Reviews:4.74.7 out of 5 stars(7,362)
Top reviews from the United States
- Collin M.Used this Brand for Both Our Children, and it Hasn't Disappointed Yet, Great Value, Great Product!These ready-to-feed bottles have been fantastic for both our newborns. We used the same brand with her older sister, and it’s been consistently reliable both times. It’s actually the same formula the hospital provided us with, and it continues to work wonderfully. We’re using it to supplement natural feeding to help with weight gain, and it’s been very effective, our baby is gaining steadily, with minimal spit-up as long as we pace her feedings. The formula flows nicely, seems very gentle on her stomach, and gives us confidence that she’s getting good nutrition. The bottles also have clear measurement markers on the side, which makes tracking very easy. The price is very reasonable for the convenience and quality. All in all, it's a trusted brand that continues to deliver, and highly recommended!
- M RomeroBaby formulaGreat product, best price I could find anywhere, and getting it delivered to your house is a plus . Bottle design with top is very practical. Great for traveling.
- saiteja“Convenient, Gentle, and Closest to Breast Milk—A Lifesaver for Busy Parents”I’ve been using the Similac 360 Total Care Ready-to-Feed 2 oz bottles (48-pack) and couldn't be more impressed.
From the start, my baby took to it wonderfully—no fussing, gas, or digestive discomfort. The bottles are utterly convenient, especially during nighttime or on-the-go feedings; there's no mixing—just open and serve—making those bleary-eyed middle-of-the-night sessions so much smoother.
What really stands out is the nutritional formulation. It features an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk, offering immune support, digestive health, and overall developmental benefits . Plus, it’s non-GMO and contains no artificial growth hormones, bringing extra peace of mind
Pros: Extremely convenient, gentle on digestion, closely mimics breast milk, immune and brain support via 5 HMO prebiotics, non-GMO, no artificial growth hormones.
Cons: Higher cost per ounce compared to powder. - ChristopherHighly recommended!We started using Similac 360 Total Care Advance when we were supplementing with formula, and it’s been a lifesaver. Our baby took to it right away — no issues with gas, fussiness, or spit-up like we experienced with a couple of other brands. It’s gentle on the tummy and seems to digest really well.
What gave us confidence is knowing it has a blend of five HMO prebiotics, designed to help support baby’s immune system — similar to what’s found in breast milk. Plus, it doesn’t have palm olein oil, which is something we were trying to avoid.
Mixes smoothly, doesn’t clump, and the powder doesn’t have a strong or unpleasant smell. Our little one has been growing well, happy, and content — and as parents, that’s all we can ask for.
Definitely recommend Similac 360 Total Care Advance to anyone looking for a high-quality, well-balanced formula that’s easy on a baby’s system. - SarahMcDermyWorth it as a first time parentThese are really convenient, especially as a first time mom. We loved them! Sadly our child had to switch formulas to a sensative brand. But it was nice while it lasted!
- Aimee MelbyConvenientI bought this when my son was a newborn. I used them as on the go and they worked perfectly. I had zero issues with quality.
- KevinConvenient Ready-to-Feed Formula That Works with Dr. Brown’s BottlesPros:
• Ready-to-feed—no mixing required
• Perfect for travel, outings, or nighttime feedings
• Works with Dr. Brown’s bottle rings and nipples
• Consistent quality and taste that baby accepts well
• Long shelf life until opened
Cons:
• More expensive than powdered formula
• Needs to be refrigerated after opening and used quickly - LuckyConvenient and Trusted—Great for Travel, Pricey for Daily UseWe’ve used Similac 360 Total Care Ready‑to‑Feed since birth, and our baby has grown well over 4 months. The 2‑oz bottles are incredibly convenient for on‑the‑go or late‑night feeds—no mixing, no mess. Like most formulas, it can cause some gassiness at times, but nothing out of the ordinary for us. The main downside is cost, so we reserve these for travel and use powder at home.
Pros:
Ready‑to‑feed bottles are perfect for travel and night feeds
Baby has grown well; no major tolerance issues
Includes 5 HMO prebiotics, designed to support immunity and digestion
Cons:
Expensive for everyday use
Occasional gas, similar to other formulas
Bottom line: A reliable, super‑convenient option that we trust—excellent for outings and emergencies, but too pricey to be our daily formula.